The boy was stabbed on the 472 bus in Woolwich Church Road just before 2.30pm yesterday (January 7).
He was treated at the scene by emergency services, but he died shortly after medics arrived.
The boy, whose full name has not yet been shared, released a song on YouTube called “Bangers N Mash” on Christmas Day.
Tributes have since poured in for the musician with friends on social media saying he was “taken too soon”.
One comment left on the teen’s Instagram reads: “Life is no joke. Once you are gone you’re gone.
“Aint no coming back. RIP.”
Another one said: “Gone but never forgotten. RIP.”
A friend of the boy told the Mirror: “That’s my friend. He’s my good friend. I used to see him after school, he didn’t deserve this.
“He was a nice person. I finished school and my mum told me he got stabbed. He was a very nice person.
“He was good at football, but I don’t think he was pursuing it as a career.”
Deputy Commander Louise Sargent described the attack as a “horrendous crime”, and said it was a “worrying time” for local residents.
She told reporters at the scene: “I’m very sad to say that this afternoon a 14-year-old boy has died.
“The initial alert was raised by a local officer out on patrol.
“Paramedics treated a 14-year-old boy at the scene who had received stab wounds, but really sadly, he died shortly after medics arrived.
“Our thoughts at this time are with the victim’s family and friends.
“This is a horrendous crime, and I can’t imagine what they must be going through right now.
“We are working at pace to identify and arrest those involved.
“I know this will be a worrying time for everyone here in Woolwich, and all the more so given the very young age of the victim.”
No arrests have been made as police enquries continue.
The incident came just 24 hours after an 18-year-old boy was left fighting for his life after stabbed outside Shooters Hill.
The teenager, a year 12 student at the college, is in a critical in hospital after the stabbing in Prince Imperial Road at around 4.20pm on January 6.
Police confirmed on Tuesday afternoon that the two stabbings were not linked.
The Mayor of London Sir Sadiq Khan said: “My thoughts are with the family, friends and wider community in Greenwich following the appalling fatal stabbing of a 14-year-old boy.
“This heart-breaking violence has absolutely no place in our city.
“I am in close contact with police leaders – an investigation is underway and local residents will see increased patrols in the local area.”
Some 10 teenagers were killed in London last year, nine of whom were the victims of stabbing while one died in a shooting, according to data compiled by the PA news agency.
This was down sharply from 21 teenage deaths in the capital in 2023.
The youngest victim in 2024 was aged 14.
If anyone witnessed the incident or has any information which may help, they are urged to call police on 101 with ref 3795/07JAN25 or call Crimestoppers anonymously.