Police were called to Waverley Road, N17, at 8.45pm on Thursday, March 20, following reports that two men had been shot.
Officers and the London Ambulance Service found a 27-year-old man with a gunshot wound to the head and a 26-year-old man with a gunshot wound to the leg.
Despite the efforts of the emergency services, the 27-year-old man died as a result of his injuries.
His family have been informed and are being supported by specialist officers.
The other man remains in hospital.
A crime scene is in place and will remain until further notice.
Enquiries are ongoing.
Anyone with information should contact police with reference CAD7426/20March or contact Crimestoppers on 0800 555 111.
Detective Chief Superintendent Caroline Haines, who leads policing in Tottenham, said: “Two men were shot on a residential street last night, with one man sadly losing his life.
“We recognise the impact this will have on the local community.
“We have multiple officers patrolling the area today, aiming to obtain key evidence and provide reassurance to you.
“At this early stage in the investigation, we have not made any arrests.
“Please do not let this worry you.
“We have a highly experienced team of investigators making urgent enquiries to find out who committed this act.
“I will now ask for anyone who was in the area, past 8pm last night, to please contact police if you heard or saw something suspicious.
“Your knowledge is crucial to us, and it may help us locate the suspects.
“Please do the right thing and come forward, you will be supported.”
