The work will affect trains from Monday (March 17) and Friday (March 21).
We have compiled all the details on these works so that you can plan your journey this week.
Engineering work is taking place overnight at various locations on the Southeastern network, closing some lines.
Monday, Wednesday and Thursday (March 17, March 19, and March 20)
The 11.20pm train from London St Pancras International to Faversham train will only run between London St Pancras International and Gravesend.
Passengers should change at Gravesend for a connecting Thameslink train to Gillingham and then change again at Gillingham for a replacement bus to Faversham calling at all stations except Teynham.
From 11.20pm until the end of service, replacement buses run between Sittingbourne and Sheerness-on-Sea.
The 11.50pm train from London St Pancras International to Faversham will be replaced by accessible buses between Ebbsfleet International, Gillingham and Faversham calling at all stations except Higham, Newington and Teynham.
Monday to Thursday (March 17 to March 20)
From 11.35pm until the end of service, replacement buses will run between Maidstone East and Ashford International.
The 10.25pm and 11.25pm trains from London Victoria to Ashford International will be diverted between Otford and Ashford International to run via Sevenoaks.
Passengers should change at Otford for a connecting service to Maidstone East, and the onward replacement bus for stations to Ashford International.
The 12.25am train from London Victoria to Ashford train will only run between Victoria and Maidstone East
Trains between London Charing Cross, London Cannon Street and Maidstone East will stop additionally at Kemsing, East Malling and Barming.
Tuesday, Thursday and Friday (March 18, March 20, and March 21)
From 12.10am until the end of service, replacement buses will run between Gillingham, Faversham and Herne Bay calling at all stations except Teynham.
A connecting train will run from Faversham to Ramsgate.
A replacement minibus will run between Sittingbourne and Teynham.
Wednesday to Friday (March 19 to March 21)
From 12.15am until the end of service, services between London Victoria and Orpington via Beckenham Junction will be diverted and run non-stop between London Victoria and Shortlands.
Replacement buses will run between Herne Hill and Orpington via Beckenham Junction, calling at all stations except Brixton, and also between Bromley South and London Victoria, calling at all stations except Brixton.
Wednesday and Thursday (March 19 to March 20)
The 11.07pm train from London St Pancras International to Ramsgate via Dover Priory will be replaced by a bus between Dover Priory and Ramsgate calling at all stations except Thanet Parkway.