The changes will take place from Monday evening until Friday morning (September 1 to September 5).
We have outlined and simplified the details so you can plan your journey.
Engineering work is taking place overnight at several locations on the Southeastern network, closing some lines.
Monday, Wednesday and Thursday (September 1, 3 and 4):
From 11.45pm until the end of service, accessible buses replace trains between Gillingham and Faversham. A connecting train will continue from Faversham to Ramsgate.
The 11.20pm and 11.50pm trains from London St Pancras International to Faversham will be replaced by buses between:
Ebbsfleet International and Gillingham calling at all stations except Higham.
Gillingham and Faversham calling at Rainham and Sittingbourne.
From 11.20pm until the end of service, replacement buses will run between Sittingbourne and Sheerness-on-Sea.
Monday to Thursday (September 1 to September 4):
From 11.45pm until the end of service, replacement buses will run between Maidstone East and Ashford International.
The 10.25pm and 11.25pm trains from London Victoria to Ashford International will be diverted between Otford and Ashford International to run via Sevenoaks.
Passengers should change at Otford for a connecting service to Maidstone East, and an onward replacement bus for stations to Ashford International.
The 12.25am train from London Victoria to Ashford International will be diverted between Otford and Ashford International to run via Sevenoaks.
Passengers should change at Sevenoaks for a replacement bus calling at Borough Green & Wrotham and all stations to Ashford International via Maidstone East.
Tuesday to Friday (September 2 to September 5):
From 12.15am until the end of service, trains between London Victoria and Orpington via Beckenham Junction will be diverted between London Victoria and Shortlands.
The 12.27am London Victoria to Orpington train will stop additionally at Denmark Hill.
Replacement buses will run from Denmark Hill to Orpington via stations on the Beckenham Junction line, and from Bromley South to London Victoria calling at all stations except Brixton.
Passengers travelling to or from Brixton can use London Underground between Victoria and Brixton at no extra cost.
Wednesday and Thursday (September 3 and 4):
The 11.07pm train from London St Pancras International to Ramsgate via Dover Priory will be replaced by a bus between Dover Priory and Ramsgate calling at all stations except Thanet Parkway.
