Jordan Vincent is wanted for the murder of Rijkaard Saifa in Fellmongers Yard near Surrey Street on Friday, April 12.
The reward of up to £10,000 is offered to anyone who has information which leads to Vincent being arrested and charged.
Detective Chief Inspector Samantha Townsend, who leads the investigation, said: “Officers have been working tirelessly on this case since April.
“While the investigation continues, we are appealing to people to dig deep into their consciences – if you have information that can help, I urge you to come forward.
“Rijkaard was only 22 and had his full life ahead of him and his family are desperate for answers – our team remains resolute in helping them secure justice and need the public’s help to do so.
“I am grateful to all those who have come forward so far but would ask anyone with information about the whereabouts of Jordon Vincent – no matter how insignificant you think it might be – to get in contact as this could prove to be crucial.”
Rijkaard Siafa died at the scene of a stabbing in Fellmongers Yard.
Two men have been charged with his murder – David Walcott, 34, of Turle Road in Norbury, and Rammon Mali, 32, of Valley Road in Kenley.
Anyone who has information or footage can call 0208 721 4961 referencing Op Biscot.