The Urban Village Fete will take place at Greenwich Peninsula on May 18, from 11am to 7pm.
The festival is expected to attract tens of thousands of people, with a programme full of performances, workshops, and activities.
BBC Radio London’s Robert Elms will host creative conversations in the Design District, and there will be 42 hands-on workshops, including ceramic tile making and a nail art workshop with celebrity artist Sophie Harris-Greenslade.
The festival will also have five bars and more than 30 food and drink stalls, as well as 32 independent designer-makers selling their creations.
New additions this year include the Brixton Ballers Wheelchair Basketball Club and Skateboard GB coach Rachael with the Keep Rolling Project.
The festival will also raise funds for War Child, the official charity partner.
Laura Flanagan, director of Greenwich Peninsula, said: “The transformation of Greenwich Peninsula since 2015 is extraordinary, and the evolution of the Urban Village Fete is just one example of how much the place has changed in a decade.
“What started as an eclectic community get-together in a brand-new piece of town, has grown into one of London’s most-loved festivals.
“Celebrating ten years of the Urban Village Fete is a significant milestone for Greenwich Peninsula, giving us the opportunity to bring to life all the very best things about living, working and visiting here in one amazing day.”
DJ Gilles Peterson said: “I played at the first ever Urban Village Fete back in 2015 and it has been incredible to watch the event grow and come together over the past 10 years.
“It is a neighbourhood that gives back to the community and that’s a special thing indeed.
“You don’t come across many other events that represent a true democratisation of art – something we need now more than ever.”
BBC Radio London presenter Robert Elms said: “Ten years ago, this part of London was little more than the O2.
“But since then, the Urban Village Fete every year has helped to promote a genuine creative quarter where people can have a great day out while enjoying art, architecture and design.
“Coming together to discuss thought-provoking topics amid a fun festival is one of the things which makes the Urban Village Fete unique.”
Wayne Hemingway of HemingwayDesign said: “HemingwayDesign takes huge pride in being able to curate and contribute to such a successful free event across the last ten years.
“Urban Village Fete gives back so much – you don’t have to spend a penny and yet you can experience something truly special.
“It is uplifting to see the vital support that Urban Village Fete gives creatives, designers, artists and small businesses.
“It brings our team incredible joy in creating something meaningful for the community, bringing people together for one unforgettable day in the heart of the city.”
The festival is located on Greenwich Peninsula, which is wrapped by the river on three sides and takes over Peninsula Square, the Design District, and the almost three-acre Central Park.
It is just two minutes from the Jubilee Line (Zone 2) North Greenwich tube station, only eight minutes from London Bridge, and accessible via Uber Boat by Thames Clippers and the IFS Cloud Cable Car.
For festival fans travelling from any valid route between Lewisham, Stratford, Newham, and Canary Wharf towards North Greenwich, travel is free via the 108 and 129 bus routes from 6.30am to 9.30pm.
