However, the Serie A giants have stumbled of late and head to Spain on the back of three successive defeats that has dented their own hopes of winning a potential treble.
Date, kick-off time and venue
Barcelona vs Inter Milan is scheduled for a 8pm BST kick-off today, Wednesday, April 30, 2025.
The first leg will take place at the Lluís Companys Olympic Stadium.
Where to watch Barcelona vs Inter Milan
TV channel: In the UK, the game will be televised live on TNT Sports.
Live stream: TNT Sports subscribers can also catch the contest live online via the Discovery+ app and website.
Live blog: You can follow all the action on matchday via Standard Sport’s live blog!
Barcelona vs Inter Milan team news
Robert Lewandowski is set to miss a third Barcelona game in a row with an injury sustained in the comeback win over Celta Vigo. Meanwhile, Alejandro Balde is also absent.
The left-back has not featured since limping off against Leganes with a hamstring issue and has not recovered in time.
Inter have suffered a massive blow after Benjamin Pavard had to be replaced in the 1-0 loss to Roma on Sunday. However, Marcus Thuram will be available for selection after missing the last three games.
Absent: Robert Lewandowski
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Barcelona vs Inter Milan prediction
Having just come through 120 minutes against Real Madrid, in addition to the emotion that comes with an El Clasico showdown, you do have to wonder what shape some of the Barcelona players are in as many looked out on their feet during extra-time.
With that said, this appears to be the perfect time to play Inter. Flick’s side rarely fail to create chances and even without Lewandowski, it would be a surprise if they didn’t take a few against a team without a clean sheet in nine.
On the other hand, Barca offer up chances which means an entertaining clash is on the cards with the hosts coming out on top.
Head to head (h2h) history and results
Barcelona vs Inter Milan match odds
Odds via Betfair (subject to change).