The changes are due to engineering work and will affect trains on Saturday and Sunday (June 21 to June 22).
We have outlined and simplified the details so you can plan your journey this weekend.
Saturday and Sunday (June 21 and June 22):
Engineering work is taking place between London Blackfriars and East Croydon or Crystal Palace, closing all lines via Sydenham.
No trains will run between London Bridge and East Croydon or Crystal Palace via Sydenham all weekend.
Replacement buses will run between New Cross Gate and Crystal Palace.
The following services will run to an amended timetable:
Trains between London Bridge and Caterham or Tattenham Corner will be diverted to run via Peckham Rye.
Trains between London Victoria and London Bridge will run between London Victoria and Crystal Palace only.
Trains will continue to run between London Victoria and Sutton or Epsom Downs.
On Saturday only, trains between East Croydon and Watford Junction will run between Clapham Junction and Watford Junction only.
Trains between London Bridge and Uckfield will run between East Croydon and Uckfield only.
Trains between London Bridge and Epsom will not run.
On Sunday, engineering work is taking place between East Croydon and Purley, closing some lines.
Until 8.30am, buses will replace trains between East Croydon, Purley, Caterham and Tattenham Corner.
Tickets will be accepted at no extra cost on Southern replacement buses between New Cross Gate and Crystal Palace, on Southern trains between Crystal Palace and East Croydon via Norwood Junction, and on London Trams or Buses by any reasonable route.