The bridge, which carries southbound traffic across the River Thames between Kent and Essex, will be shut from 10pm to 5.30am for essential maintenance.
Southbound vehicles will be diverted through the East Tunnel in a contraflow system.
This is part of a wider programme of overnight closures affecting both directions at the Dartford Crossing from Thursday, July 11 through to the early hours of Monday, July 14.
The crossing, used by over 150,000 vehicles each day, is one of the UK’s busiest road routes and a vital freight and commuter link between the southeast and the rest of the country.
National Highways said diversions will be clearly signposted via their network and local roads.
Friday, July 11 – Saturday, July 12
A282-Northbound
A282 Northbound Dartford Crossing West Tunnel closure
East Tunnel closure for joint replacement works 11pm – 6am
Diversion via National Highways network
Saturday, July 12 – Sunday, July 13
A282-Clockwise
A282 Southbound QEII bridge
Bridge closure for bridge works 10pm – 5.30am
Diversion via east tunnel contraflow
A282-Northbound
A282 Dartford Crossing East Tunnel
Northbound carriageway closure 9.30pm – 5am
Diversion via Highways England Network
A282-Southbound
A282 Southbound Jct 1A exit slip road closure
A282 Southbound Jct 1A Exit slip road closure for white lining works 10pm – 6am
Diversion via National Highways Network
Sunday, July 13 – Monday, July 14
A282-Northbound
A282 Dartford Crossing East Tunnel
Northbound carriageway closure 10pm – 6am
Diversion via Highways England Network
