The incident happened just outside Dagenham East Underground station around 2.50pm yesterday (March 13).
Officers found a van had hit a pedestrian at the junction of Shafter Road and Rainham Road South.
Paramedics were called to help a 37-year-old man who suffered “severe” injuries which are thought to be life-changing, but not life-threatening.
AS IT HAPPENED: Rainham Road Dagenham station incident
He is in hospital undergoing treatment.
The ambulance service reported that a second person was also injured and taken to hospital.
There have been no arrests while a police investigation is ongoing.
A Metropolitan Police spokesperson said: “Police were called at 14:49hrs on Thursday, 13 March to reports of a road traffic collision outside Dagenham East Station.
“Officers attended the scene at the junction of Shafter Road and Rainham Road South, and called for assistance of London Ambulance Service, after a large van had been in collision with a pedestrian.
“A 37-year-old man suffered severe injuries in the incident, which are said to be life-changing, but not life-threatening. He has been taken to hospital for further treatment.
“No arrests have been made. Enquiries are ongoing.
“If you were a witness or have any information which may help, please call 101 with the reference 4302/13Mar.”
A London Ambulance Service spokesperson said: “We were called at 2.50pm today (13 March) to reports of a road traffic collision near Dagenham East Underground Station, in Rainham Road South.
“We sent resources to the scene including an ambulance crew, a paramedic in a fast response car and an incident response officer to the scene.
“We treated two patients at the scene and took them both to hospital.”
The London Fire Brigade also attended the incident.
A spokesperson said: “Crews were called to reports of a road traffic collision on Rainham Road South in Dagenham.
“One man was taken to hospital.
“Control Officers took the call at 1453 and mobilised three fire engines and a Fire Rescue Unit to the scene. The incident was over for firefighters at 1521.”
