Ace Café, on the North Circular Road near Stonebridge, is taking action to deter antisocial behaviour in the area.
Established in 1938, it has been a popular site for bikers to visit and hang out with each other.
However the café has enforced new rules to close four and a half hours earlier than expected on Fridays.
The café announced: “As a consequence of illegal and unacceptable behaviour on the road, the Ace will close on Fridays at 6pm until further notice.
“Thanking you in advance for your support and understanding.”
It has added: “Illegal and unacceptable behaviour will result in exclusion or barring from the café.
“The use of controlled drugs including cannabis will not be allowed anywhere on our premises or in the car park.
“Vehicles not displaying a number plate, or an illegal plate, will not be allowed in the car park.
“Wheelies, burn outs, loud revving of engines will not be tolerated in our car park or on the road.”
Normally, Ace Cafe is open every day from 8am to 10.30pm.