The site lies on the border of Greenwich and Bexley and is located just north of Abbey Wood station.
It is on the corner of Eynsham Drive and the A2041 and is currently home to a car wash and Thamesmead PDSA Pet Hospital.
Abbey Wood Property Limited submitted the scheme in early 2024 and it consists of four buildings that range from a 17-storey tower block to a three-storey building.
As part of the proposal both the car wash and the pet hospital will be demolished, but a larger, more modern facility for the pet hospital is being provided.
A PDSA spokesperson said: “We have been involved in discussions regarding the development around our Thamesmead PDSA Pet Hospital.
“Now plans have been approved, we are working through implications and options for our site and our team whilst the extensive building works are underway.
“We remain committed to providing PDSA services to the communities we serve, and the Thamesmead PDSA Pet Hospital will continue to open as normal while we confirm the longer-term plan.”
Instead of providing self-contained flats, the scheme will deliver 487 co-living rooms.
The co-living rooms consist of a bedroom with an ensuite bathroom, a small kitchenette and integrated storage space.
The rooms will measure from 18 to 24 square metres.
Co-living, which developers have called a “high-quality solution for urban renters” is meant to encourage social interaction amongst residents through communal areas like large dining areas and kitchens, gyms, co-working spaces, and gardens.
These co-living units will be offered at flexible lease lengths from three to 12 months and will have all-inclusive contracts that covers bills and a gym membership.
According to planning documents, these types of units are aimed at young professionals as an alternative to HMOs and smaller apartments.
Alongside the co-living residential units, the new scheme will deliver a 110-room hotel which is likely to be a Holiday Inn Express.
This application was made on the back of another proposal at the site that was approved in 2018.
This proposal, which was similar in visual terms to the final outcome, would have delivered 272 flats instead of the 487 co-living rooms.