The major terminus will be closed between December 25 and January 1.
Network Rail will be replacing ageing roof panels, Greater Anglia said.
The Bishopsgate Tunnel will also undergo essential maintenance.
This means many services to and from London will terminate at or start from Stratford.
Connections to central London can be made via the Elizabeth line and London Underground services.
There will be changes on the Underground as on days when Liverpool Street station is closed, ticket acceptance has been arranged on the Elizabeth line and Central line between Stratford and London Liverpool Street, on the Victoria line between Tottenham Hale and King’s Cross St Pancras, and on the Circle, Hammersmith & City line, and Metropolitan lines between King’s Cross St Pancras and London Liverpool Street.
Martin Beable, Greater Anglia’s managing director, said: “Since the railway tends to be much quieter over this period, Network Rail uses it to carry out essential upgrade work that will help Greater Anglia to continue operating a very punctual and reliable service for customers in 2026.
“We apologise for the inconvenience caused by the service alterations, and we urge passengers to check before they travel as some journeys may take longer than normal.”
Passengers should also be aware that some services will be retimed.
Details can be found via the journey planner on the Greater Anglia website or app.
