Kent Police applied for the closure of the home on Willow Road on October 8 and have now secured the property.
Dartford Borough Council have since applied to the court for possession of the property.
The closure order will last for three months and any unauthorised person entering the property during this time could face a fine and a prison sentence.
A notice has been placed on the door with a warning that it is an offence to enter.
Police Sergeant Rob Wilkinson said: “Residents and visitors to the area have suffered anti-social behaviour and incidents of disorder involving those using this premises for some time.
“They raised concerns with their local constables and council enforcement officers, who warned the occupants of the consequences if they continued.
“Their behaviour failed to improve and we have now put in place prohibitive measures to address this.”
PS Wilkinson added: “We work closely with the local authority to tackle disorderly behaviour that can affect the quality of life for residents.
“Any other people who choose to pursue an anti-social and often criminal lifestyle can expect similar consequences.”