The event, which takes place at Battersea Park on Saturday, June 14, is the charity’s flagship walking event.
The 63-year-old actor, known for his roles in Batman Begins and The Dark Knight, was diagnosed with prostate cancer in 2022.
He has since become an advocate for the cause, inspiring many to check their risk.
Prostate cancer survivors and supporters to walk together in Battersea on June 14 (Image: Prostate Cancer UK) Mr McFarlane will be walking alongside theatre director Femi Elufowoju Jr OBE, who was motivated to see his GP after watching Mr McFarlane on BBC television two years ago.
Mr Elufowoju Jr was diagnosed with prostate cancer in December 2023.
Mr McFarlane said: “I absolutely love Prostate Cancer UK’s March for Men, and it’s wonderful to return for a third year.
“From friends and loved ones to complete strangers, this event brings so many people together for a vitally important cause.
“Some are celebrating, others are remembering, but you are never alone.
“Prostate cancer affects one in eight men, and those stats increase to one in four if you are Black, like me.
“So my passion for spreading awareness and saving lives remains as strong as ever.”
Prostate cancer is the most common cancer in men, affecting thousands of men across the UK.
In London alone, more than 38,000 men are living with the disease.
Prostate Cancer UK’s flagship event offers music, food, and family fun in the park (Image: Prostate Cancer UK)
Mr Elufowoju Jr said: “I’m so grateful I switched on the TV that day and am indebted to Colin for saving my life.”
Mr McFarlane added: “Meeting so many people who have been affected by prostate cancer over the past few years and speaking to some who continue to be influenced by me sharing my own story, old friends and new, is incredibly humbling.
“It also inspires me to do more.
“It’s empowering to know that your words really can save lives.”
The March for Men event allows participants to stroll 2.5km, 5km, or 10km around Battersea Park.
The event is open to all ages and abilities, including families, friendship groups, work colleagues, and dogs.
There will be musical entertainment on the route, a scavenger hunt for kids and adults, and much more to do in the event village, including food and refreshments.
Laura Kerby, chief executive at Prostate Cancer UK, said: “Our slogan is ‘it’s so much more than a walk in the park’, and that is so true.
“We are really proud of March for Men; it’s such a special event and it never disappoints, and we thank Colin and everyone taking part.
“Once again, we can’t wait to welcome our wonderful supporters, joining together in their thousands, to walk towards a better future for men.
“And with every step taken we will make a huge difference to everyone affected by this disease.”
Since the March for Men launched in 2017, around 17,000 Prostate Cancer UK supporters have come together to raise £3 million to help fund lifesaving research and support men and their families navigating this disease.