The incident happened in Dagenham Road near Eastbrook School just before 1.30pm today (April 17).
Officers and London Ambulance Service crews were called to the scene.
LIVE as yellow tent erected with cordons in place at bus stop in Dagenham
An ambulance crew, an advanced paramedic, an incident response officer and a clinical team manager also attended.
The man was pronounced dead at the scene shortly after.
We have contacted Metropolitan Police for further information.
A spokesperson for London Ambulance Service said: “We were called at 1.28pm today (17 April) to reports of a person unwell on Dagenham Road, Dagenham.
“We sent resources to the scene, including an ambulance crew, an advanced paramedic, an incident response officer and a clinical team manager.
“Our first paramedics arrived on scene in less than four minutes.
“Sadly, despite the best efforts of our crews, a man was pronounced dead at the scene.”