Diversions will be in place via National Highways routes, but motorists are advised to plan ahead to avoid potential delays.
The closures, which affect both northbound traffic, are subject to change depending on weather conditions.
The Dartford Crossing, which connects Dartford in Kent to Thurrock in Essex via the A282, is a key transport route over the River Thames.
Friday, April 11 – Saturday, April 12
A282-Northbound
A282 northbound Dartford Crossing West Tunnel
Tunnel closure for maintenance works 11pm – 6am
Diversion via National Highways network
Saturday, April, April 12 – Sunday, April 13
A282-Northbound
A282 northbound Dartford Crossing West Tunnel
Tunnel closure for maintenance works 10pm – 5.30am
Diversion via National Highways network
Sunday, April 13 – Monday, April 14
A282-Northbound
A282 northbound Dartford Crossing East Tunnel
Tunnel closure for maintenance works 10pm – 5am
Diversion via National Highways network