The Birmingham favourite had originally been scheduled to begin his comeback against Jack Della Maddalena, only for the Australian to be pulled from the fight as he instead now faces Muhammad for the title at UFC 315 in Montreal in May.
Edwards now takes on American Brady, the UFC’s fifth-ranked welterweight who has back-to-back wins over Kelvin Gastelum and Gilbert Burns to his name since suffering his own stoppage defeat to Muhammad at UFC 280 in Abu Dhabi in October 2022.
McCann is also on the main card, hoping to reassert some authority after losing three of her last four fights including against Bruna Brasil in Manchester last July. She was originally supposed to battle Istela Nunes, only for the latter to be replaced at short notice by fellow Brazilian strawweight and UFC debutant Alexia Thainara.
London featherweight Nathaniel Wood will look to build on his win over Daniel Pineda in Manchester as he meets France’s Morgan Charriere, followed by an all-British showdown between England’s Jordan Vucenic and Chris Duncan from Scotland.
Other home fighters in action on the night include Jai Herbert, Lone’er Kavanagh, Mick Parkin, Christian Leroy Duncan and Nathan Fletcher, plus Irish duo Shauna Bannon and Caolan Loughran.
Title lost: Leon Edwards was defeated by Belal Muhammad at UFC 304 in Manchester last summer
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There’s also a showdown on the main card between former light-heavyweight champion Jan Blachowicz and Carlos Ulberg, while Gunnar Nelson fights Kevin Holland at welterweight.
UFC London date and venue
UFC London – also known as UFC Fight Night: Edwards vs Brady or just UFC Fight Night 255 – will take place tonight on Saturday March 22, 2025.
The event once again is hosted at the O2 Arena.
UFC London schedule and start time
The preliminary fights at UFC London are expected to begin at 5pm GMT, which is 1pm ET and 10am PT in the United States.
The main card should get underway from 8pm GMT, which is 4pm ET and 1pm PT. Edwards vs Brady should take place at approximately 10pm GMT, 6pm ET and 3pm PT.
Leon Edwards vs Sean Brady
Jan Blachowicz vs Carlos Ulberg
Gunnar Nelson vs Kevin Holland
Molly McCann vs Alexia Thainara
Jordan Vucenic vs Chris Duncan
Nathaniel Wood vs Morgan Charriere
Jai Herbert vs Chris Padilla
Lone’er Kavanagh vs Felipe dos Santos
Marcin Tybura vs Mick Parkin
Christian Leroy Duncan vs Andrey Pulyaev
Shauna Bannon vs Puja Tomar
Nathan Fletcher vs Caolan Loughran
Guram Kutateladze vs Kaue Fernandes
Comeback needed: ‘Meatball’ Molly McCann has lost three of her last four fights in the UFC
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TV channel: In the UK, UFC London is being shown live tonight on TNT Sports. Coverage of the prelim bouts begins at 5pm GMT on TNT Sports 2, with the main card available to watch on both TNT Sports 1 and TNT Sports 2 from 8pm GMT.
Live stream: TNT Sports subscribers can also watch live online via the Discovery+ app and website.
In the US, the event is being shown live on ESPN+. Subscribers to UFC Fight Pass can also watch the prelims there.
Live blog: You can also follow the octagon action as it happens on Saturday night with Standard Sport’s live blog.
Nathaniel Wood to win: 6/5
Jordan Vucenic to win: 1/4
Chris Duncan to win: 11/4
Odds via Betfair (subject to change).
