It is Manchester City, however, who kick-off the action this weekend when Pep Guardiola takes his side to high-flying Nottingham Forest on Saturday lunchtime.
Liverpool are then in action at 3pm GMT later that day, as Arne Slot’s side welcome the struggling Southampton.
Three points could open up a 16-point gap on Premier League title rivals Arsenal, who do not play until Sunday.
Elsewhere on Saturday, Crystal Palace host the struggling Ipswich and Fulham head down to Brighton. Brentford, meanwhile, entertain Aston Villa in the later kick-off.
On Sunday, the action ramps up again. Enzo Maresca’s Chelsea welcome his former club Leicester and Tottenham square off against Bournemouth.