High Road, Willesden was taped up by police from the morning of yesterday (December 28) and most of today (December 29) as forensics investigated the knife attack.
Police were called to reports of a stabbing in Linacre Road, just off the High Road, at 4.16am.
They were dispatched to the scene with the London Ambulance Service and air ambulance, where a man was found with serious stab wounds.
He was taken to hospital but is understood to have died at Edgware Road before arriving there.
Police at Willesden Green (Image: NQ)
Investigating officers are confident that the victim was a male in his 30s, though formal identification is yet to take place.
A parade of shops on the High Road were unable to open for the last two days due to the crime scene.
The Brent & Kilburn Times understands this was finally lifted at around 9pm today (December 29).
Work is underway to identify his next of kin, who will be supported by specialist officers.
The Metropolitan Police has not shared any information on if arrests have been made, but enquires are ongoing.
Anyone with information that could assist police is asked to call 101 or contact @MetCC on X quoting reference 1013/28DEC.
Alternatively, information can also be provided anonymously to the independent charity Crimestoppers on 0800 555 111.