Emergency services were called to John Harrison Way in Greenwich yesterday (July 5) at around 4:50am, after a crash involving a car and a pedestrian.
A 46-year-old woman was treated by paramedics at the scene before being taken to hospital.
The force has confirmed that her injuries have been assessed as life-changing.
A 29-year-old man was arrested at the scene on suspicion of grievous bodily harm and currently remains in police custody.
Police are continuing to make enquiries into the incident.
A spokesperson for Metropolitan Police said: “Around 04:50hrs on Saturday, 5 July, officers attended John Harrison Way, SE10, alongside the London Ambulance Service following reports of a collision between a car and a pedestrian.
“A 46-year-old woman was treated at the scene by paramedics. She was taken to hospital, where her injuries were assessed as life-changing.
“A 29-year-old man was arrested at the scene on suspicion of grievous bodily harm. He was taken into police custody, where he remains.
“Enquiries continue.
“Anyone with information is asked to call police on 101, quoting reference CAD1679/05JUL. You can also contact Crimestoppers anonymously on 0800 555 111.”
