Finalists two seasons ago and the reigning Italian champions, Inter are also yet to taste defeat in Europe thus far.
San Siro is undoubtedly one of the most iconic grounds in world football and Arsenal can really gauge their progress under Mikel Arteta while up against such a big challenge.
Here’s everything you need to know.
Date, kick-off time and venue
San Siro in Milan will host.
Where to watch Inter Milan vs Arsenal
TV channel: The game will be broadcast on TNT Sports 1.
Live stream: Subscribers will be able to watch on a live stream via the Discovery+ app.
LIVE coverage: Follow all the action with Standard Sport’s dedicated match blog!
Inter Milan vs Arsenal team news
Gunners captain Martin Odegaard is hoping to return in time for the trip to Milan, though Takehiro Tomiyasu, Riccardo Calafiori and Kieran Tierney are not expected to feature.
Inter Milan vs Arsenal prediction
It’s a difficult task for Arsenal but their defensive solidity and the fact Inter also won’t want to risk a defeat suggests a draw is reasonably likely.
Head to head (h2h) history and results
Inter Milan vs Arsenal latest odds
Inter Milan to win: 17/10
Odds via Betfair and subject to change.