The incident is believed to have taken place on a train from London Kings Cross to Hull shortly after 7.30pm today (November 1).
Armed officers attended and the train was stopped at Huntingdon, where two men were arrested.
A number of people have been taken to hospital.
A spokesperson for Cambridgeshire Police said: “We were called at 7.39pm with reports that multiple people had been stabbed on a train.
“Armed officers attended and the train was stopped at Huntingdon, where two men were arrested. A number of people have been taken to hospital.
“The incident remains ongoing and the A1307 has been closed as you approach the town centre.
“Officers are working with British Transport Police, who are leading on the incident, and anyone with any information is urged to report this to us online.”
A spokesperson for the British Transport Police said: “We are currently responding to an incident on a train to Huntingdon where multiple people have been stabbed.
“Officers are in attendance alongside Cambridgeshire Police and two people have been arrested.”
This is a breaking news story. More to follow.

