Should the Red Devils pick up three points in west London, they will have recorded back-to-back Premier League wins for the first time under the Portuguese tactician.
The Bees won the corresponding fixture last season 4-3, though much has changed since with new head coach Keith Andrews making a solid start as Thomas Frank’s replacement.
Here’s everything you need to know about where to watch the match…
How to watch Brentford vs Manchester United
TV channel: In the UK, the game will be televised live on TNT Sports. Coverage starts at 11am BST on TNT Sports 1 ahead of the 12.30pm kick-off.
Live stream: TNT Sports subscribers can also catch the contest live online via the Discovery+ app and website.
Free highlights: Match of the Day broadcasts on Saturday, September 27, 2025 on BBC One at 10.30pm BST.
