Spurs have little else left to play for this season, with European glory the only thing that could still salvage the season.
Ange Postecoglou’s side should be considered one of the favourites for the competition, particularly given key players are soon expected to return from injury.
Still, supporters are unlikely to get too excited just yet, with the team on a famously long trophy drought.
If they can reach the quarter-finals, however, then momentum could really start to grow.
It’s likely to be a hostile environment for Spurs in the Netherlands. Alkmaar smashed Galatasaray last time out in order to reach this stage, so are certainly not to be overlooked.
Troy Parrott, of course, is a former Spurs player and would no doubt love to prove a few people wrong by making an impact against the Premier League giants.
Postecoglou believes his side sense an opportunity to win something. Now, they have to go out and prove it.
With that in mind, here’s a look at all you need to know about where to watch the game.
How to watch Tottenham vs AZ Alkmaar
TV channel: In the UK, the game will be televised live on TNT Sports 3. Coverage starts at 5pm GMT ahead of a 5.45pm kick-off.
Live stream: Fans can catch the contest live online via the Discovery+ app and website.
Live blog: You can follow all the action on matchday via Standard Sport’s live blog, with expert analysis from Dan Kilpatrick at the ground.