The men from South Croydon, Pinner and West Drayton are among four who were charged after raids in in Hertfordshire and London last Wednesday (April 23).
Essex Police had reports of a drug line operating from London which sold the class A drugs to the streets of Southend.
Three warrants were executed on the day, resulting in four arrests along with mobile phones and cannabis seized.
Kaelan Stafford, 20, of Selsdon Park Road in South Croydon, was charged with conspiring to supply class A drugs and being concerned in the supply of a class B drugs.
Dillon Flemming,18, of Pinner, was charged with conspiring to supply class A drugs, being concerned with the supply of a class B drug and possessing with intent to supply a class B drug.
Junior Brown, 20, of Drayton Gardens in West Drayton, was charged with conspiring to supply class A drugs.
Jay Taylor, 25 of Mill End in Rickmansworth, was charged with conspiring to supply class A drugs and being concerned in the supply of a class B drugs.
All four remain in custody and are due to appear at Basildon Crown Court on May 22.
Detective Chief Inspector Neal Miller said: “Each drug line identified, disrupted and eventually dismantled by my officers is another step taken towards eliminating knife crime, disorder and anti-social behaviour on the streets of Southend and Basildon.
“Incidents of violence involving weapons on our streets remain rare, and typically we find they are confined to criminal groups known to each other.
“We know how important it is for the public to see and understand that we’re working hard to stamp out the wider supply of drugs fuelling this unacceptable behaviour.”