Emergency services were called to Marlowe Way at 10.15am today (January 23), where the incident happened outside the Argos distribution centre, near the Asda Wallington Superstore.
London Ambulance Service treated five people at the scene. One was taken to a major trauma centre in London, while four others were transported to local hospitals.
Police remain at the scene alongside the London Ambulance Service.
A 54-year-old man was among those hospitalised, with police confirming that his injuries are not life-threatening.
One man has been arrested in connection with the incident.
A London Ambulance Service spokesperson said: “We were called at 10.21am this morning (Thursday 23 January) to reports of a stabbing incident in Marlowe Way, Croydon.
“We sent several resources to the scene, including ambulance crews, a paramedic in a fast response car, an incident response officer, members of our Tactical Response Unit and London’s Air Ambulance.
“Our crews treated five patients at the scene, before taking one to a London major trauma centre and four to other hospitals.”
A spokesperson for the Metropolitan Police said: “At 10.15am on Thursday, January 23, officers responded to reports of a stabbing at a commercial address on Marlowe Way, Beddington
“Officers are on scene with the London Ambulance Service to treat four injured people.
“A 54-year-old man was taken to hospital where his injuries were deemed non-life-threatening.”
“One man has been arrested.”