Enzo Maresca’s side are unbeaten this term after two wins and one draw, most recently beating Fulham 2-0 at Stamford Bridge thanks to Joao Pedro and Enzo Fernandez’s goals.
Brentford, meanwhile, have had a mixed start to the campaign, winning two of their four games in all competitions.
They have beaten Aston Villa and Bournemouth, but lost to Nottingham Forest and Sunderland in the opening fixtures of Keith Andrews’ reign.
They will be without Yoane Wissa, who completed a move to Newcastle United before the transfer deadline.
Date, kick-off time and venue
Brentford vs Chelsea is scheduled for an 8pm BST kick-off on Saturday, September 13, 2025.
The match will take place at the Gtech Community Stadium, in west London.
Where to watch Brentford vs Chelsea
TV channel: In the UK, the game will be televised live on Sky Sports Main Event and Sky Sports Premier League, with coverage following West Ham vs Tottenham.
Live stream: Sky Sports subscribers can also catch the contest live online via the Sky Go app and website.
Live blog: You can follow all the action on matchday via Standard Sport’s live blog.
Free highlights: The Sky Sports app and YouTube channel will show highlights after the game, before Match of the Day airs on BBC One at 10.20pm BST.
Brentford vs Chelsea team news
Chelsea’s main worry is their talisman Cole Palmer.
The attacking midfielder was withdrawn from the starting XI before their 5-1 win over West Ham, and he remained sidelined for the victory against Fulham.
He was not involved for England over the international break, although it remains to be seen whether he will be fit to return here.
Benoit Badiashile and Romeo Lavia are other fitness concerns for Maresca, while Liam Delap and Dario Essugo will both be longer-term absentees.
As for Brentford, Vitaly Janelt and Paris Maghoma remain out in the engine room, although Yunus Emre Konak and Gustavo Nunes could be in line for returns.
Brentford vs Chelsea prediction
The world champions have looked very good in their last two games following a disappointing showing against Crystal Palace on the opening day.
That has even been without Palmer, and they racked up the goals against West Ham before putting in a solid display against their west London rivals last time out.
Brentford are a tough nut to crack at home, but the Blues are in good form and should have enough to defeat their neighbours here.
Head to head (h2h) history and results
Brentford vs Chelsea match odds
Odds via Betfair (subject to change).
