The Reds were beaten by Eddie Nketiah’s late winner at Selhurst Park over the weekend, falling to their first league defeat of the campaign.
Arne Slot’s side still sit two points clear at the top of the table, having won all five of their other games in the English top flight.
In Europe, however, they were taken 12 rounds by Atletico Madrid on matchday one, needing an injury-time header from Virgil van Dijk to seal all three points against the La Liga outfit.
Andy Robertson and Mohamed Salah’s quickfire double salvo inside six minutes made many think that the Premier League champions would run riot at Anfield, but they were pegged back by Marcos Llorente’s brace.
That was until van Dijk rose highest to power home past Jan Oblak to secure a dramatic victory.
Galatasaray, meanwhile, were thrashed 5-1 in their opening Champions League game by Eintracht Frankfurt.
As such, the Super Lig side will be looking to harness their raucous home support to drum up an intimidating atmosphere for their Premier League opponents here.
Date, kick-off time and venue
Galatasaray vs Liverpool is scheduled for an 8pm BST kick off on Tuesday, September 30, 2025.
The match will take place at RAMS Park in Istanbul.
Where to watch Galatasaray vs Liverpool
TV channel: In the UK, the game is not on television.
Live stream: Instead, the match will be streamed live on Amazon Prime, with kick off at 8pm BST. Coverage will begin at 7pm.
Galatasaray vs Liverpool team news
Neither side have any serious injury concerns heading into this clash.
For the hosts, star striker Victor Osimhen made his return to action in a 1-0 victory over Alanyaspor on Friday having sustained an ankle injury on international duty with Nigeria.
Gala manager Okan Buruk said that he wanted Osimhen to “play for 10 minutes “and “experience the pain”, emphasising that “playing through pain is important”.
The Turkish side are so anxious to get their talisman back fit and firing that Buruk has tinkered his formation and tried to rush Osimhen back ahead of schedule.
“We may have changed our formation and had trouble covering the opposition,” he said.
“However, we’re taking these risks to ensure he plays.”
Galatasaray vs Liverpool prediction
If Osimhen is not fully fit, that will give Liverpool more confidence in their chances of escaping a tempestuous atmosphere with victory.
The fact that Slot will be able to name a full-strength lineup will be welcome news to the Reds, who should have enough quality to put their Turkish opponents to the sword here.
Head to head (h2h) history and results
Galatasaray vs Liverpool match odds
Odds via Betfair (subject to change).