For the Dutch side to progress, they have to win by seven clear goals. A task that seems highly unlikely given that Arsenal have only conceded four goals in the entire competition so far this season.
Still, the north London outfit will have to guard against complacency to some degree as they look to finish the job and set up a quarter-final clash with either Real Madrid or Atletico Madrid.
Date, kick-off time and venue
The match will take place at the Emirates Stadium.
Where to watch Arsenal vs PSV
TV channel: In the UK, the game will be televised live on TNT Sports 2. Coverage starts at 7pm GMT ahead of an 8pm kick-off.
Live stream: Fans can catch the contest live online via the Discovery+ app and website.
Live blog: You can follow all the action on matchday via Standard Sport’s live blog, with expert analysis from Simon Collings at the ground.
Ben White could make his first Arsenal start in months against PSV
Arsenal FC via Getty Images
With a healthy lead in the bag, Arteta may have one eye on Sunday’s Premier League encounter against Chelsea and therefore opt to rotate his Arsenal team for the second leg.
Gabriel Martinelli made his return from injury as a second half substitute in the draw with Man Utd, but it may be too soon for him to start.
PSV will once again be without former Arsenal forward Lucas Perez as he is ineligible, Ricardo Pepi is a long-term injury absentee but Sergino Dest is available after making his long-awaited return from a serious knee injury at the weekend.
Arsenal vs PSV prediction
It’s hard to see PSV being as poor as they were in the first leg. Whilst the tie is ultimately beyond them, they have nothing to lose and will surely be out to give a better account of themselves.
If they sit deep and look to frustrate Arsenal, it could work in their favour as the Gunners have struggled against deep blocks in recent weeks.
However, Arteta’s side seem to save their best attacking performances for the Champions League and whatever team he selects should have enough to claim victory, though another big scoreline seems unlikely.
Head to head (h2h) history and results
Arsenal vs PSV match odds
Odds via Betfair (subject to change).
